Four Ph. D Positions are available for 2024-January Session
Research Interest
Transition Metal Catalyzed C‒H Functionalization of Privileged bioactive Scaffolds
The reliable and predictable conversion of a C–H into a C–C, C–N, C–O, or C–X bond in a selective and controlled way is beneficial in terms of step economy and waste reduction. Considering the easy availability of alkanes in nature, the C‒H bond functionalization strategy could provide practical processes for the synthesis of fine chemical via inexpensive methods. Novel methods for C–H activation extend the number of sites that can be targeted in a given molecule, increasing the opportunity to elaborate it into a more complex natural products and pharmaceutical compounds. We aim to develop regioselective C-H bond transformation via directing group based strategy.
Enantioselective Organocatalysis and Total Synthesis of Bioactive Alkaloids
Encouraged by the biosynthetic pathway we are involved in the enantioselective synthesis of izidine alkaloids using organocatalytic approach. The pathway has also been explored to develop reaction methodologies that enable synthesis of unnatural izidine substrates.
